Clenbuterol: What is it Used For + Side Effects & Dangers SelfDecode Drugs

Another study involving rats on a protein-restricted diet revealed that clenbuterol can hasten the recovery of muscle mass following malnutrition (7). There has yet to be any published research that links clenbuterol to being directly responsible for muscle enlargement in healthy humans (8). However, human studies do suggest that long-acting systemic beta 2-agonists can increase muscle size in specific muscle fibers. But this long-term effect may be so gradual that it goes unnoticed in healthy users. This cycle uses an advanced compound called T3 (Cytomel), a thyroid hormone.

• The US is one exception, so no pharmaceutical-grade Clenbuterol is sold in the United States.
• In animals given doses far greater than those required to relax the airways, clenbuterol reduced fat mass more than other fat burners, like ephedrine.
• Women using Clenbuterol run the risk of fertility complications and disrupting the menstrual cycle.
• This cycle uses an advanced compound called T3 (Cytomel), a thyroid hormone.

The following is a summary of the available research on clenbuterol, much of which was conducted before the dangers of the drug were fully clarified. A study on tissues showed that clenbuterol increases levels of a genetic regulator (histone demethylase JHDM2a) by activating beta-2 receptors (via protein kinase A pathway). This regulator controls metabolic (and other related) genes, which ultimately decreases the size of fat cells 15. In our experience, men and women typically lose 10–15 pounds from a 4-week cycle of clenbuterol. Winstrol is an oral compound like clenbuterol; however, it is highly https://ngoctung.com/2024/12/19/stanozolol-before-and-after-understanding-its-2/ hepatotoxic.

User Experiences & Abuse

Unlike with anabolic steroids, the dosage of clenbuterol is the same for men and women. This is because it affects the CNS rather than working on a hormonal level (where women have significantly less testosterone and thus need smaller doses of steroids to obtain the same level of results). Clenbuterol has a stimulating effect on beta-2 adrenergic receptors, which can affect satiety levels in humans. Consequently, our patients have reported decreased hunger throughout the day, despite burning more calories.

How long does Clen take to work?

In Australia, most of Europe and the U.S., this drug can legally be used to treat breathing problems in horses. However, Oklahoma State’s Dr. Michael Davis studied this subject and determined that clen has no performance-enhancing effect on horses. Clenbuterol is approved as a therapeutic drug for treating asthma in Bulgaria, China and Russia. However, despite its usefulness as a bronchodilator, clen has not been approved for treating human breathing disorders in many other countries. While clenbuterol doesn’t increase heart rate as much as adrenaline, the natural substance that it mimics, this is still a side effect that users need to worry about. So it’s recommended that users monitor their heart rate to ensure that it stays within a safe range ( resting BPM).

Some find that the stimulant side effects, even at the lowest doses, are too harsh to handle, while others can use Clen at the higher end of the dosage range with few noticeable side effects. It has become famous as a fat loss agent, and people unfamiliar with the history or medical use of this drug could easily think that fat loss is the reason Clenbuterol exists. Clen has high bioavailability at up to 98% and avoids first-pass metabolism11.

There’s no safe time to use Clenbuterol for performance and fat loss because there will always be risks at any dose and time. Clenbuterol is a highly potent drug, so starting your dosage low and scaling it up slowly throughout the cycle is essential. Therapeutic and clinical study doses are typically 20mcg to 40mcg per day. Clenbuterol’s ability to make it easier to remove this fat allows competitors to have significantly better muscle definition that might otherwise be masked by overlaying fat. In serious competitions, every ounce of fat counts, and the most serious competitors will often add to Clen’s effects by stacking it with powerful fat-burning anabolic steroids like Winstrol. Clenbuterol’s fat-burning abilities can be considered just an offshoot from its original purpose as a bronchodilator for asthmatics.

Clenbuterol induces growth, prevents breakdown, and speeds recovery of muscles. It stimulates protein production within cells, which eventually increases muscle mass (via beta-2 activation) 8, 9. According to some studies, more than 80% of people who abused clenbuterol and experienced significant adverse effects had to be hospitalized. People who have never used clenbuterol before are more likely to have adverse effects than those who have. The use of clenbuterol is not approved for human use in the United States because it may cause permanent damage to essential organs, and some nations consider its usage to be illegal.

19 people with chronic heart failure treated with clenbuterol (randomized controlled trial) had a significant increase in lean muscle and lean-to-fat ratio. Despite the fact that clenbuterol has not been approved for human usage in many countries (even as an asthma drug), it is widely used across the world as a weight-loss aid. When reviewing two U.S. poison control centers, a 2013 study noted that 11 of the 13 cases involving clenbuterol stemmed from bodybuilding and/or weight-loss use (12). Even in countries where it’s illegal, clen remains popular among athletes, bodybuilders, celebrities and for enlarging livestock. Clenbuterol has been shown to have a positive anabolic effect in various species of animals. For example, clen increased the size of skeletal muscle fiber in rats in utero (6).